Cost Calculator

for calculating biobanking costs

Welcome to the BBMRI-LPC cost calculator!

BBMRI-LPC (Biobanking and Biomolecular Resources Research Infrastructure – Large Prospective Cohorts) is one of the largest biobanking networks in Europe aiming to facilitate scientists’ access to large prospective study sets on human health and disease. Find more information on BBMRI-LPC here.

The BBMRI-LPC cost calculator is a tool that enables biobanks to calculate their biobanking associated costs. This shall help them to determine a price strategy for their samples, data and services. The cost calculator has been designed for population based cohorts and biobanking in clinical studies. It has a modular design and is based on a process-oriented view. That means it takes you through the whole chain from survey/study preparation to delivery of samples and data. First experiences indicated that it takes about an hour to complete if all required information is available at the time of completing the survey.

Please start the calculation with the module “General” and fill all the fields there, as these are required for the calculations later on. All calculations used in the cost calculator are listed under “formula” for your information. You can save the data you enter in the cost calculator by clicking on the green button “save” – which allows you to save the data to a file on your computer - and reload them later on for further calculations or changes. The data you enter do not leave your computer as all calculations are performed locally in your browser - therefore they are kept absolutely confidential.

For cohorts participating in BBMRI-LPC we will collect data on a voluntary basis to evaluate and analyze biobanking costs in Europe. Non BBMRI-LPC biobanks are of course very welcome to join – so if you would like to participate, please contact us at: Contact

Additionally, we feel that costs in biobanking are an important topic that needs to be discussed widely and open to find solutions for sustainable funding of biobanks. Therefore we also plan to provide the possibility to put your data in an open access database that can be viewed by anyone else who has put their data into the database. This can be done anonymously, but we ask you to provide the country, where the biobank is run, as e.g. personnel costs vary a lot between countries and the data will then be more informative for the users.

We hope you find this tool useful and would like to know about your experiences: For comments, suggestion or questions, please contact us at: Contact

please indicate the per hour cost (gross cost including overhead costs for personnel if applicable) for a person with the following profesional level
academic
G1
requiring dedicated education
G2
without special education
G3

what is the percentage of overhead costs you apply ?
G4
how many years of depreciation do you commonly calculate?
G5
what is the percentage of gross costs you calculate maintentance costs with in general?
G6

which currency unit do you use?
G7
please indicate the name of your survey
People involved in the preparation of this survey (for sample aquisition planning)?
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please indicate for every involved person the estimated number of working hours Cost for one person
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S10
Persons involved in the conduction of the survey (administrative personnel, study nurses, doctors)
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please indicate for every involved person the estimated number of working hours Cost for one person
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S12

are there any additional costs for the survey, e.g. mailings, costs for scheduling probands, adress verification etc., please indicate amount per survey
S6

do you pay your probands a compensation fee or similar (like travel expenses)? Please indicate amount per proband
S7

how many probands are included in the survey?
S8

S13

if applicable, please indicate transportation costs for transport of samples from the study center to the laboratory for the complete survey
S6a
S14

S15

how many aliquots do you collect on average per proband (one aliquot corresponds to 200 ul Serum, Plasma, Urine or 1 ug DNA)
S16

S17
Is there additional personal not named in the module "survey costs" working on sample processing? Please indicate number of staff involved
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the processing of the samples of one survey Cost for one person per year
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per year
P4
please indicate the costs for consumables for one proband for blood sampling and processing (infusion set, blood tubes, centrifugation tube, gloves etc.)
P5
please indicate the costs for consumables for one proband for urine sampling and processing (urine beaker, centrifugation tube, gloves etc.)
P6
please indicate the cost for one aliquot tube for plasma/serum/urine including rack and labels
P7
how many aliquots of plasma, serum and urine do you collect on average per proband (please count every single entity that you put to storage as one aliquot)
P8
P9
P10
P11
P12
please indicate the number of samples for which you would like to calculate the DNA extraction costs (e.g. one, ten, number of samples in a complete survey)
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for DNA extraction and quality control Cost for one person
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D5
please indicate the costs for consumables for DNA extraction (extraction kits or consumables for manual extraction)
D6
please indicate the costs for consumables for DNA quality control (PCR kits, DNA gels)
D7
D8
D9
how many DNA aliqutos do you get out of one sample?
D10
please indicate the cost for one DNA aliquot tube?
D12
D11
for the calculation of personnel costs for transfer of samples to storage, please indicate the number of aliquots for which you would like to calculate this
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for transferring the number aliquots from question 1 to storage and documentation Cost for one person
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ST5

if applicable, please indicate transportation costs for transport of samples from the laboratory to the storage device (biorepository) for the number of aliquots from question 1
ST5a
ST6
ST6a
how many -20°C freezer do you have in use for your biobank
ST7
what are the gross costs to purchase one -20°C freezer
ST8
per year
ST9
per year
ST10
per year
ST11
how many -80°C freezer do you have in use for your biobank
ST12
what are the gross costs to purchase one -80°C freezer
ST13
per year
ST14
per year
ST15
per year
ST16
how many nitrogen tanks do you have in use for your biobank
ST17
what are the gross costs to purchase one nitrogen tank
ST18
per year
ST19
per year
ST20
per year
ST21
how many -80°C automated storage systems do you have in use for your biobank
ST22
if you share the system, to what percentage do you use this automated storage systems for your biobank
ST23
what are the gross costs to purchase one -80°C automated storage system
ST24
per year
ST25
per year
ST26
per year
ST27
how many -180°C automated storage systems do you have in use for your biobank
ST28
if you share the system, to what percentage do you use this automated storage systems for your biobank
ST29
what are the gross costs to purchase one -180°C automated storage system
ST30
per year
ST31
per year
ST32
per year
ST33
what are your electricity costs for all freezers per year?
ST34
what are the costs for nitrogen for the tanks per year?
ST35
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours per year for vigilance and emergencies Cost for one person
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ST39
do you have any vigilance systems in use for your storage systems? Please indicate gross cost for this system for all your storage devices
ST40
per year
ST41
per year
ST42
per year
ST43
do you have an external provider for vigilance and emergencies? Please indicate yearly costs for this service
ST44
how many aliquots do you currently store in all your storage devices
ST45
per year
ST46
per year
ST47
ST48
for the following calculation, please indicate the number of aliquots for which you would like to calculate
SP1
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for picking the number of aliquots from question 1 and documentation Cost for one person
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SP5
SP6
for the following calculation, please indicate the number of aliquots for which you would like to calculate
SP7
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for aliquoting and quality control Cost for one person
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SP11
SP12

What are the additional costs for consumables for sample retrieval (e.g. dry ice), aliquoting/emptying straws and quality control for the indicated number of aliquots?
SP13
SP14
for the following calculation, please indicate the number of aliquots for which you would like to calculate
SP15
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for packing samples Cost for one person
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SP19
SP20

what are the costs for packing material for the indicated number of aliquots?
SP21
SP22
please indicate the costs for shipment of the number of samples indicated above (in number of aliquots) on dry ice within Europe
SP25

SP23
based on the number of aliquots entered above
SP26
based on the number of issued aliquots per year entered in section Biobank Processes
SP24
please indicate the name of your survey
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the preparation of one survey (only part additional to sample survey) Cost for one person
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PD5
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the conduction of one survey (only for data acquisition) Cost for one person
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PD9
are there any additional costs for the survey, e.g. mailings, costs for scheduling probands, adress verification etc., please indicate amount(only if additional to sample survey)
PD10
Do you pay your probands a compensation fee or similar? Please indicate amount per proband (only if additional to sample survey)
PD11
how many probands are included in the survey?
PD12
PD13

do you use special equipment for data acquisition, e.g. MRI, x-Ray, lung function measurements etc., please list name and gross cost for every item
Name ... please name the item (optional) Gross Cost ... please list gross cost for every item
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for how many months is this equipment in exclusive use for the survey?
PD10b
PD10c

per year
PD10d

per year
PD10e
PD10f
are there consumable costs for data acquisition (e.g. ultrasound gel), please lindicate costs for one survey
PD10g
instead of using own equipment, do you pay for services for data acquistion, like MRT, x-Ray etc.? Please indicate total costs for one survey
PD10h

Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the ingression of the data in a database Cost for one person
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PD17
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the quality control of the data Cost for one person
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PD21
are there any additional costs related to the proband data (e.g. costs for servers, software, external data management service)? Please indicate amount for one survey or indicate these costs under “Biobank Processes"
PD22
PD23
PD24
please indicate the number of probands for which you would like to calculate the costs for data compilation
PD25
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please estimate for every involved person the number of working hours for the data compilation Cost for one person
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PD29
PD30
People that are involved in adminstrative and supportive processes in your biobank (administrative: marketing, fund raising, administration of personnel, supportive: IT management, quality management)
Name please indicate the name of the person (optional) Qualification level please indicate for every involved person the qualification level Number of working hours please indicate for every involved person the estimated number of working hours for the administration of the biobank per year Cost for one person per year
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per year
BP4
besides freezer and tanks, what other laboratory equipment exists in your biobank, e.g. pipeting robots, DNA extraction robots, LIMS systems or other IT infrastructure? Please list name and gross cost for every item.
Name ... please name the item (optional) Gross Cost ... please list gross cost for every item
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BP6

per year
BP7

per year
BP8

How many aliquots do you on average issue per year?
BP9

per year
BP10

per year
BP11

per year
BP12

BP13
for more details press "Show Details" button, please

CS1

CS2

CS3

CS4

CS7

CS5

CS6
CS8
CS9

CS10
CS11
CS12

ID Calulation Formula Description
Summary
CS1 S17+P12+SP23+ST6a one aliquot of serum, plasma or urine without storage (w/o overheads)
CS2 S17+D11+SP23+ST6a One aliquot of DNA (w/o overheads)
CS3 ST48 = (ST11+ST16+ST21+ST27+ST33+ST34+ST35+ST39+ST43+ST44)/ST45 Storage of one aliquot per year
CS4 BP13 = (BP7+BP8+BP4)/BP9 Biobank processes per aliquot issued per year
CS5 PD24 = (PD5+PD9+PD10+PD10f+PD10g+PD10h+PD13+PD17+PD21+PD22)/PD12 Data ingression costs per proband per dataset
CS6 PD30 = PD29/PD25 Data compilation for projects per proband
CS7 SP25/SP15 Sample shipment per aliquot
CS8 S14+P9 One survey for biosamples (preparation, sampling, sample processing)
CS9 P7*P8*S8 Aliquot vials for one survey
CS10 ST6a*S16*S8 Transport to storage for aliquots of one survey
CS11 PD23 One survey for data (acquisition, ingression and quality control)
CS12 ST47+BP12 Yearly running costs (without survey conduction)
Survey
S13 S7*S8 Expenses for all probands
S14 S10+S12+S6+S13 Survey costs
S15 S14/S8 Survey costs per proband
S17 S15/S16 Survey costs per aliquot
Sampling
P9 P4+P5*S8+P6*S8+S6a Processing costs for survey
P10 P9/S8 Processing costs per proband
P11 P10/P8 Processing costs per aliquot
P12 P11+P7 Processing costs per aliquot + tube cost
DNA Extraction
D8 D5+D6+D7 DNA extraction and quality control costs
D9 D8/D1 DNA extraction costs per sample
D11 D9/D10 DNA extraction and quality control costs per aliquot
Sample Storage
ST6 ST5/ST1 Working costs transfer to storage / aliquot
ST6a (ST5+ST5a)/ST1 Total costs transfer to storage / aliquot
ST46 ST11+ST16+ST21+ST27+ST33+ST34+ST35 Total costs for storage devices per year
ST47 ST46+ST39+St43+St44 Total costs storage per year
St48 ST47/ST45 Storage costs per aliquot per year
Sample Retrieval
SP23 SP6+SP12+SP14+SP20+SP22 Total costs sample retrieval, quality control and packing / aliquot
SP26 Sp25/Sp15 Sample shipment / aliquot
SP24 SP23*BP9 Total costs sample retrieval, quality control and packing for all aliquots issued per year
Proband Data
PD23 PD5+PD9+PD10+PD10f+PD10g+PD10h+PD13+PD17+PD21+PD22 Data acquisition, ingression, quality control for one survey
PD24 PD23/PD12 Data acquisition, ingression, quality control for one proband (data of one survey)
PD30 PD29/PD25 Data compilation for projects per proband
Biobank Processes
BP11 BP10/BP9 Costs for additional equipment / issued aliquot / year
BP12 BP10+BP4 Total costs for biobank processes / year
BP13 BP12/BP9 Total costs for biobank processes / issued aliquot