Publications 2004 - today
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Selected publications which refer to KORA and KORA-gen
- Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, Nikolov I, Hamshere M, Jones I, Czerski PM, Leszczynska-Rodziewicz A, Kapelski P, Bogaert AV, Illig T, Hauser J, Maier W, Berrettini W, Byerley W, Coryell W, Gershon ES, Kelsoe JR, McInnis MG, Murphy DL, Nurnberger JI, Reich T, Scheftner W, O'Donovan MC, Propping P, Owen MJ, Rietschel M, Nothen MM, McMahon FJ, Craddock N
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.
Nat Genet. 2004 Aug;36(8):783-4 - Geller F, Reichwald K, Dempfle A, Illig T, Vollmert C, Herpertz S, Siffert W, Platzer M, Hess C, Gudermann T, Biebermann H, Wichmann HE, Schafer H, Hinney A, Hebebrand J
Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.
Am J Hum Genet. 2004 Mar;74(3):572-81 - Gohlke H, Illig T, Bahnweg M, Klopp N, Andre E, Altmuller J, Herbon N, Werner M, Knapp M, Pescollderungg L, Boner A, Malerba G, Pignatti PF, Wjst M
Association of the interleukin-1 receptor antagonist gene with asthma.
Am J Respir Crit Care Med. 2004 Jun 1;169(11):1217-23 - Illig T, Bongardt F, Schopfer A, Muller-Scholze S, Rathmann W, Koenig W, Thorand B, Vollmert C, Holle R, Kolb H, Herder C, Kooperative Gesundheitsforschung im Raum Augsburg/Cooperative Research in the Region of Augsburg
Significant association of the interleukin-6 gene polymorphisms C-174G and A-598G with type 2 diabetes.
J Clin Endocrinol Metab. 2004 Oct;89(10):5053-8 - Justenhoven C, Hamann U, Pesch B, Harth V, Rabstein S, Baisch C, Vollmert C, Illig T, Ko YD, Bruning T, Brauch H
ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population.
Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2059-64 - Riemenschneider M, Klopp N, Xiang W, Wagenpfeil S, Vollmert C, Muller U, Forstl H, Illig T, Kretzschmar H, Kurz A
Prion protein codon 129 polymorphism and risk of Alzheimer disease.
Neurology. 2004 Jul 27;63(2):364-6 - Schedel M, Carr D, Klopp N, Woitsch B, Illig T, Stachel D, Schmid I, Fritzsch C, Weiland SK, von Mutius E, Kabesch M
A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels.
J Allergy Clin Immunol. 2004 Nov;114(5):1100-5 - Vollmert C, Illig T, Altmuller J, Klugbauer S, Loesgen S, Dumitrescu L, Wjst M
Single nucleotide polymorphism screening and association analysis--exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthma.
Clin Exp Allergy. 2004 Dec;34(12):1841-50 - Weidinger S, Klopp N, Wagenpfeil S, Rummler L, Schedel M, Kabesch M, Schafer T, Darsow U, Jakob T, Behrendt H, Wichmann HE, Ring J, Illig T
Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults.
J Med Genet. 2004 Sep;41(9):658-63 - Fischer M, Lieb W, Marold D, Berthold M, Baessler A, Loewel H, Hense HW, Hengstenberg C, Holmer S, Schunkert H, Erdmann J
Lack of association of a 9 bp insertion/deletion polymorphism within the bradykinin 2 receptor gene with myocardial infarction.
Clin Sci (Lond). 2004 Nov;107(5):505-11 - Lieb W, Pavlik R, Erdmann J, Mayer B, Holmer SR, Fischer M, Baessler A, Hengstenberg C, Loewel H, Doering A, Riegger GA, Schunkert H
No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors.
Int J Cardiol. 2004 Nov;97(2):205-12 - Illig T, Vollmert C, Gohlke H, Klopp N, GSF Forschungszentrum fuer Umwelt und Gesundheit, Neuherberg
Hochdurchsatz SNP Genotypisierung mit MALDI TOF MS.
BIOspektrum 2004 May - Baessler A, Hasinoff MJ, Fischer M, Reinhard W, Sonnenberg GE, Olivier M, Erdmann J, Schunkert H, Doering A, Jacob HJ, Comuzzie AG, Kissebah AH, Kwitek AE
Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity.
Diabetes. 2005 Jan;54(1):259-67. - Doering A, Meisinger C, Thorand B, Loewel H, for the MONICA/KORA study group
Ernährungsverhalten und Übergewicht: Untersuchungen in den MONICA/KORA-Studien. Diet and obesity: Investigations in the MONICA/KORA studies.
Gesundheitswesen 2005; 67. - Heid IM, Lamina C, Bongardt F, Fischer G, Klopp N, Huth C, Kuechenhoff H, Kronenberg F, Wichmann HE, Illig T
Wie gut können Haplotypen in den populationsbasierten KORA Studien rekonstruiert werden? How About the Uncertainty in the Haplotypes in the Population-Based KORA Studies?
Gesundheitswesen 2005; 67. - Heid IM, Vollmert C, Hinney A, Doering A, Geller F, Loewel H, Wichmann HE, Illig T, Hebebrand J, Kronenberg F, KORA group
Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys.
J Med Genet. 2005 Apr;42(4):e21. - Herder C, Illig T, Rathmann W, Martin S, Haastert B, Moeller-Scholze S, Holle R, Thorand B, Koenig W, Wichmann HE, Kolb H, for the KORA study group
Inflammation and Type 2 Diabetes: Results from KORA Augsburg. Entzündung und Typ 2 Diabetes: Ergebnisse von KORA Augsburg.
Gesundheitswesen 2005; 67 - Holle R, Happich M, Loewel H, Wichmann HE, for the KORA study group
KORA - A research platform for population based health research. KORA - Eine Forschungsplattform für bevölkerungsbezogene Gesundheitsforschung.
Gesundheitswesen 2005; 67. - Hysi P, Kabesch M, Moffatt MF, Schedel M, Carr D, Zhang Y, Boardman B, von Mutius E, Weiland SK, Leupold W, Fritzsch C, Klopp N, Musk AW, James A, Nunez G, Inohara N, Cookson WO
NOD1 variation, immunoglobulin E and asthma.
Hum Mol Genet. 2005 Apr 1;14(7):935-41. - Illig T, Bongardt F, Schoepfer-Wendels A, Huth C, Heid IM, Rathmann W, Martin S, Vollmert C, Holle R, Thorand B, Wichmann HE, Koenig W, Kolb H, Herder C, for the MONICA/KORA study group
Genetics of Type 2 Diabetes: Impact of Interleukin-6 Gene Variants. Genetik von Typ 2 Diabetes: Einfluss von Interleukin-6 Genvarianten.
Gesundheitswesen 2005; 67. - Jaremko M, Justenhoven C, Abraham BK, Schroth W, Fritz P, Brod S, Vollmert C, Illig T, Brauch H
MALDI-TOF MS and TaqMan assisted SNP genotyping of DNA isolated from formalin-fixed and paraffin-embedded tissues (FFPET).
Hum Mutat. 2005 Mar;25(3):232-8. - Kamm C, Healy DG, Quinn NP, Wullner U, Moller JC, Schols L, Geser F, Burk K, Borglum AD, Pellecchia MT, Tolosa E, Del Sorbo F, Nilsson C, Bandmann O, Sharma M, Mayer P, Gasteiger M, Haworth A, Ozawa T, Lees AJ, Short J, Giunti P, Holinski-Feder E, Illig T, Wichmann HE, Wenning GK, Wood NW, Gasser T
The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA study group
Brain. 2005 Jun 9. - Koenig W, Meisinger C, Baumert J, Khuseyinova N, Loewel H
Systemic Low-Grade Inflammation and Risk of Coronary Heart Disease: Results from the MONICA/KORA-Augsburg Cohort Studies. Systemische Entzündung und Risiko für eine koronare Herzkrankheit: Ergebnisse der MONICA/KORA Augsburg Kohortenstudien.
Gesundheitswesen 2005; 67. - Kormann MS, Carr D, Klopp N, Illig T, Leupold W, Fritzsch C, Weiland SK, von Mutius E, Kabesch M
G-Protein-coupled Receptor Polymorphisms Are Associated with Asthma in a Large German Population.
Am J Respir Crit Care Med. 2005 Jun 15;171(12):1358-62. - Kuch B, Schunkert H, Muscholl M, Doering A, vScheidt W, Hense H-W, for the MONICA/KORA study group
Verteilung, Determinanten und Referenzwerte linksventrikulrer Parameter in der Allgemeinbevölkerung - Resultate der MONICA/KORA Echokardiographiestudien. Distribution, determinants and reference values of left ventricular parameters in the general population - results of the MONICA/KORA studies on Echocardiography.
Gesundheitswesen 2005; 67 - Lamina C, Steffens M, Mueller J, Lohmussaar E, Meitinger T, Wichmann HE
Genetic diversity in German and European populations: Looking for substructures and genetic patterns. Genetische Diversität in deutschen und europäischen Bevölkerungen: Suche nach Substrukturen und genetischen Mustern.
Gesundheitswesen 2005; 67. - Lamina C, Meisinger C, Heid IM, Rantner B, Doering A, Loewel H, Wichmann HE, Kronenberg F
Ankle-Brachial Index and Peripheral Arterial Disease. Knöchel-Arm-Index und periphere arterielle Verschlusskrankheit.
Gesundheitswesen 2005; 67. - Lederbogen F, Deuschle M, for the MONICA/KORA study group
Dysfunktion des Hypothalamus - Hypophysen - Nebennierenrinden - Systems - Hintergrundvariable relevanter kardiovaskulärer Risikofaktoren? Beschreibung eines kooperativen Projektes. Dysfunction of hypothalamus-hypophysis-adrenal cortex-system - Background variable of relevant cardiovascular risk factors? Description of a cooperative project.
Gesundheitswesen 2005; 67. - Loehmussaar E, Gschwendtner A, Mueller JC, Org T, Wichmann HE, Hamann G, Meitinger T, Dichgans M
ALOX5AP gene and the PDE4D gene in a central European population of stroke patients.
Stroke. 2005 Apr;36(4):731-6- - Loewel H, Meisinger C, Heier M, Hoermann A
The population-based Acute Myocardial Infarction (AMI) Registry of the MONICA/KORA study region of Augsburg. Das bevölkerungsbezogene Herzinfarktregister der MONICA/KORA Studienregion Augsburg.
Gesundheitswesen 2005; 67 - Loewel H, Doering A, Schneider A, Heier M, Thorand B, Meisinger C, for the MONICA/KORA study group
The MONICA Augsburg surveys - basis for prospective cohort studies. Die MONICA Augsburg Surveys - Grundlage für prospektive Kohortenstudien.
Gesundheitswesen 2005; 67. - Meisinger C, Doering A, Heier M, Thorand B, Loewel H, for the MONICA/KORA study group
Type 2 Diabetes mellitus in Augsburg - an epidemiological overview. Typ 2 Diabetes in Augsburg - ein epidemiologischer Überblick.
Gesundheitswesen 2005; 67. - Mostafazadeh A, Herder C, Haastert B, Hanifi-Moghaddam P, Schloot N, Koenig W, Illig T, Thorand B, Holle R, Eslami MB, Kolb H, KORA group
Association of humoral immunity to human Hsp60 with the IL-6 gene polymorphism C-174G in patients with type 2 diabetes and controls.
Horm Metab Res. 2005 Apr;37(4):257-63. - Mueller JC, Fuchs J, Hofer A, Zimprich A, Lichtner P, Illig T, Berg D, Wullner U, Meitinger T, Gasser T
Multiple regions of alpha-synuclein are associated with Parkinsons disease.
Ann Neurol. 2005 Apr;57(4):535-41. - Mueller JC, Lohmussaar E, Magi R, Remm M, Bettecken T, Lichtner P, Biskup S, Illig T, Pfeufer A, Luedemann J, Schreiber S, Pramstaller P, Pichler I, Romeo G, Gaddi A, Testa A, Wichmann HE, Metspalu A, Meitinger T
Linkage disequilibrium patterns and tagSNP transferability among European populations.
Am J Hum Genet. 2005 Mar;76(3):387-98. - Pfeufer A, Jalizadeh S, Perz S, Mueller JC, Hinterseer M, Illig T, Akyol M, Huth C, Schoepfer-Wendels A, Kuch B, Steinbeck G, Holle R, Naebauer M, Wichmann HE, Meitinger T, Kaeaeb S
Common Variants in Myocardial Ion Channel Genes Modify the QT Interval in the General Population: Results From the KORA Study.
Circulation Research 96: 693-701, 2005 - Rathmann W, Haastert B, Icks A, Herder C, Kolb H, Holle R, Mielck A, Meisinger C, Wichmann HE, Giani G
The Diabetes Epidemic in the Elderly Population in Western Europe: Data from Population-Based Studies. Die Diabetes-Epidemie in der älteren Bevölkerung in Westeuropa: Daten aus bevölkerungsbasierten Studien.
Gesundheitswesen 2005; 67. - Schumacher J, Abou Jamra R, Becker T, Klopp N, Franke P, Jacob C, Sand P, Fritze J, Ohlraun S, Schulze TG, Rietschel M, Illig T, Propping P, Cichon S, Deckert J, Noethen MM
Investigation of the DAOA/G30 locus in panic disorder.
Mol Psychiatry. 2005 May;10(5):428-9. - Thorand B, Schneider A, Baumert J, Doering A, Marowsky-Koeppl M, Heier M, Meisinger C, Loewel H
Case-cohort studies: an effective design for the investigation of biomarkers as risk factors for chronic diseases--demonstrated by the example of the MONICA/KORA Augsburg Case-Cohort Study 1984-2002. Fall-Kohorten-Studien: Ein effektives Design zur Untersuchung von Biomarkern als Risikofaktoren für chronische Krankheiten - Darstellung am Beispiel der MONICA/KORA Augsburg Fall-Kohorten Studie 1984-2002.
Gesundheitswesen 2005; 67. - Thorand B, Kolb H, Baumert J, Koenig W, Chambless L, Meisinger C, Illig T, Martin S, Herder C
Elevated Levels of Interleukin-18 Predict the Development of Type 2 Diabetes Mellitus Results From the MONICA/KORA Augsburg Study 1984-2002, 2005,
Diabetes, in press - Wichmann HE, Gieger C, Illig T, for the KORA study group
KORA-gen - Resource for population genetics, controls and a broad spectrum of disease phenotypes. KORA-gen - Ressource für Bevölkerungsgenetik, Kontrolle und ein breites Spektrum an Krankheitsphänotypen.
Gesundheitswesen 2005; 67. - Weidinger S, Klopp N, Rummler L, Wagenpfeil S, Novak N, Baurecht H-J, Groer W, Darsow U, Heinrich J, Gauger A, Schafer T, Jakob T, Behrendt H, Wichmann HE, Ring J, Illig T
Association of NOD1 polymorphisms with atopic eczema and related phenotypes.
Journal of Allergy and Clinical Immunology 2005 Jul 116(1):177-84 - Weidinger S, Klopp N, Wagenpfeil S, Roemmler L, Baurecht HJ, Fischer G, Holle R, Jakob T, Darsow U, Schoefer T, Behrendt H, Ring J, Illig T
Association study of mast cell chymase polymorphisms with atopy.
Allergy 2005. - Weidinger S, Klopp N, Roemmler L, Wagenpfeil S, Baurecht HJ, Gauger A, Darsow U, Jakob T, Novak N, Schoefer T, Heinrich J, Behrendt H, Wichmann HE, Ring J, Illig T, for the KORA study group
Association of CARD 15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults.
Clinical & Experimental Allergy 2005 Jul; 35(7): 866-72 - Wermter AK, Reichwald K, Buch T, Geller F, Platzer C, Huse K, Hess C, Remschmidt H, Gudermann T, Preibisch G, Siegfried W, Goldschmidt HP, Li WD, Price RA, Biebermann H, Krude H, Vollmert C, Wichmann HE, Illig T, Sorensen TI, Astrup A, Larsen LH, Pedersen O, Eberle D, Clement K, Blundell J, Wabitsch M, Schafer H, Platzer M, Hinney A, Hebebrand J
Mutation analysis of the MCHR1 gene in human obesity.
Eur. J. Endocrinol.152:851-862 (2005) - Schulze TG, Ohlraun S , Czerski PM , Schumacher J, Heidmann V, Kovalenko S, Abou Jamra R, Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, Henn FA, McMahon FJ, Maier W, Propping P, Noethen MM , Rietschel M
Are bipolar patients with and without persecutory delusions genetically distinct? Results from a phenotype-genotype correlation analysis on the G72/G30 locus.
2005 Am J Psychiat, 162:2101-8. - Glaser B, Schumacher J, Williams HJ, Jamra RA, Ianakiev N, Milev R, Ohlraun S, Schulze TG, Czerski PM, Hauser J, Jonsson EG, Sedvall GC, Klopp N, Illig T, Becker T, Propping P, Williams NM, Cichon S, Kirov G, Rietschel M, Murphy KC, O'Donovan MC, Noethen MM, Owen MJ
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biol Psychiatry. 2005 Jul 1;58(1):78-80. - Justenhoven C, Hamann U, Pierl CB, Rabstein S, Pesch B, Harth V, Baisch C, Vollmert C, Illig T, Bruning T, Ko Y, Brauch H
One-carbon metabolism and breast cancer risk: no association of MTHFR, MTR, and TYMS polymorphisms in the GENICA study from Germany.
Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):3015-8. - Biskup S, Mueller J, Sharma M, Lichtner P, Zimprich A, Berg D, Woellner U, Illig T, Meitinger T, Gasser T
Common variants of LRRK2 (PARK8) are not associated with sporadic Parkinson disease.
2005, Annals of Neurology, 58(6):905-8. - Rabstein S, Unfried K, Ranft U, Illig T, Kolz M, Rihs HP, Mambetova C, Vlad M, Bruning T, Pesch B
Variation of the N-acetyltransferase 2 gene in a romanian and a kyrgyz population.
Cancer Epidemiol Biomarkers Prev. 2006 Jan;15(1):138-41. - Gohlke H, Illig T, Klopp N, Wagenpfeil S, Maljkovic L, Laws SM, Kurz A, Riemenschneider M
Association study between the D10S1423 microsatellite marker and Alzheimer's disease.
2005, Neurobiol Aging in press. - Mackevics V, Heid IM, Wagner S, Cip P, Doppelmayr H, Lejnieks A, Gohlke H, Ladurner G, Illig T, Iglseder B, Kronenberg F, Paulweber B
The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.
European Journal of Human Genetics, in press. - Kschischo M, Kern R, Gieger C, Steinhauser M, Tolle R
Automatic scoring and quality assessment using accuracy bounds for FP-TDI SNP genotyping data.
Appl Bioinformatics. 2005;4(2):75-84. - Berg D, Schweitzer K, Leitner P, Zimprich A, Lichtner P, Belcredi P, Brussel T, Schulte C, Maass S, Nagele T
Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease.
Brain. 2005 Dec;128(Pt 12):3000-11. - Schnittger S, Kohl TM , Leopold N, Schoch C, Wichmann HE, Kern W, Lohse P, Hiddemann W, Haferlach T, Spiekermann K
D324N single-nucleotide polymorphism in the FLT3 gene is associated with higher risk of myeloid leukemias
Genes, Chromosomes and Cancer, 2005. - Herder C, Haastert B, Muller-Scholze S, Koenig W, Thorand B, Holle R, Wichmann HE, Scherbaum WA, Martin S, Kolb H
Association of Systemic Chemokine Concentrations With Impaired Glucose Tolerance and Type 2 Diabetes: Results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4).
Diabetes. 2005; 54(suppl 2):S11-S17. - Rashid MU, Jakubowska A, Justenhoven C, Harth V, Pesch B, Baisch C, Pierl CB, Bruning T, Ko Y, Benner A, Wichmann HE, Brauch H, Hamann U, GENICA Network
German populations with infrequent CHEK2*1100delC and minor associations with early-onset and familial breast cancer.
Eur J Cancer. 2005 Dec;41(18):2896-903. - Wichmann HE
Genetic Epidemiology in Germany. From Biobanking to Genetic Statistics.
Methods Inf Med 4, 584-589 (2005). - Schumacher J, Abou Jamra R, Becker T, Ohlraun S, Klopp N, Binder E, Schulze TG, Deschner M, Braeman C, Hoefels S, Zobel A, Illig T, Propping P, Holsboer F, Rietschel M, Noethen MM, Cichon S
Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression.
Biol Psychiatry 58, 307-314 (2005). - Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marban E, O'Donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
Nature Genetics, 2006 Jun;38(6):644-51. - Vollmert C, Windl O, Xiang W, Rosenberger A, Zerr I, Wichmann HE, Bickeboller H, Illig T, KORA group, Kretzschmar HA
Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study.
J Med Genet. 2006 Oct;43(10):e53. - Weidinger S, Novak N, Klopp N, Baurecht H, Wagenpfeil S, Rummler L, Ring J, Behrendt H, Illig T
Lack of association between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema.
Journal of Allergy and Clinical Immunology (JACI), 2006 Jul;118(1):277-9. - Herder C, Muller-Scholze S, Rating P, Koenig W, Thorand B, Haastert B, Holle R, Illig T, Rathmann W, Seissler J, Wichmann HE, Kolb H
Systemic monocyte chemoattractant protein-1 concentrations are independent of type 2 diabetes or parameters of obesity: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4).
Eur J Endocrinol. 2006 Feb;154(2):311-7. - Metzger MH, Heier M, Maki M, Bravi E, Schneider A, Loewel H, Illig T, Schuppan D, Wichmann HE
Mortality excess in individuals with elevated IgA anti-transglutaminase antibodies: the KORA/MONICA Augsburg cohort study 1989-1998.
Eur J Epidemiol. 2006;21(5):359-65. Epub 2006 Apr 29. - Hinney A, Bettecken T, Tarnow P, Brumm H, Reichwald K, Lichtner P, Scherag A, Nguyen TT, Schlumberger P, Rief W, Vollmert C, Illig T, Wichmann HE, Schafer H, Platzer M, Biebermann H, Meitinger T, Hebebrand J
Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany.
J Clin Endocrinol Metab. 2006 May;91(5):1761-9. - Schedel M, Depner M, Schoen C, Weiland SK, Vogelberg C, Niggemann B, Lau S, Illig T, Klopp N, Wahn U, von Mutius E, Nickel R, Kabesch M
The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations.
Respir Res. 2006 Jun 19;7:91. - Grallert H, Huth C, Kolz M, Meisinger C, Herder C, Strassburger K, Giani G, Wichmann HE, Adamski J, Illig T, Rathmann W
IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4.
Exp Gerontol. 2006 Aug;41(8):737-45. - Fernandez-Santiago R, Sharma M, Mueller JC, Gohlke H, Illig T, Anneser J, Munch C, Ludolph A, Kamm C, Gasser T
Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.
Neurology. 2006 Jun 27;66(12):1929-31. - Jamra RA, Villela AW, Klein K, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S, Rietschel M, Noethen MM, Schumacher J
No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia.
Psychiatr Genet. 2006 Jun;16(3):91. - Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CN, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Noethen MM, McLean WH, Novak N
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.
J Allergy Clin Immunol. 2006 Jul;118(1):214-9. Epub 2006 Jun 9. Erratum in: J Allergy Clin Immunol. 2006 Oct;118(4):922. J Allergy Clin Immunol. 2006 Sep;118(3):724. - Riemenschneider M, Konta L, Friedrich P, Schwarz S, Taddei K, Neff F, Padovani A, Kolsch H, Laws SM, Klopp N, Bickeboller H, Wagenpfeil S, Mueller JC, Rosenberger A, Diehl-Schmid J, Archetti S, Lautenschlager N, Borroni B, Muller U, Illig T, Heun R, Egensperger R, Schlegel J, Forstl H, Martins RN, Kurz A
A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.
Hum Mol Genet. 2006 Aug 15;15(16):2446-56. - Jamra RA, Klein K, Villela AW, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S, Rietschel M, Noethen MM, Schumacher J
Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder.
Am J Med Genet B Neuropsychiatr Genet. 2006 Sep 5;141(6):663-5. - Kamm C, Asmus F, Mueller J, Mayer P, Sharma M, Muller UJ, Beckert S, Ehling R, Illig T, Wichmann HE, Poewe W, Mueller JC, Gasser T
Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.
Neurology. 2006 Nov 28;67(10):1857-9. - Huth C, Heid IM, Vollmert C, Gieger C, Grallert H, Wolford JK, Langer B, Thorand B, Klopp N, Hamid YH, Pedersen O, Hansen T, Lyssenko V, Groop L, Meisinger C, Doring A, Loewel H, Lieb W, Hengstenberg C, Rathmann W, Martin S, Stephens JW, Ireland H, Mather H, Miller GJ, Stringham HM, Boehnke M, Tuomilehto J, Boeing H, Mohlig M, Spranger J, Pfeiffer A, Wernstedt I, Niklason A, Lopez-Bermejo A, Fernandez-Real JM, Hanson RL, Gallart L, Vendrell J, Tsiavou A, Hatziagelaki E, Humphries SE, Wichmann HE, Herder C, Illig T
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants data from 21 studies.
Diabetes. 2006 Oct;55(10):2915-21. - Steffens M, Lamina C, Illig T, Bettecken T, Vogler R, Entz P, Suk EK, Toliat MR, Klopp N, Caliebe A, Konig IR, Kohler K, Ludemann J, Diaz Lacava A, Fimmers R, Lichtner P, Ziegler A, Wolf A, Krawczak M, Nurnberg P, Hampe J, Schreiber S, Meitinger T, Wichmann HE, Roeder K, Wienker TF, Baur MP
SNP-based analysis of genetic substructure in the German population.
Hum Hered. 2006;62(1):20-9. Epub 2006 Sep 21. - Georgi A, Jamra RA, Schumacher J, Becker T, Schmael C, Deschner M, Hofels S, Wulff M, Schwarz M, Klopp N, Illig T, Propping P, Cichon S, Noethen MM, Rietschel M, Schulze TG
No association between genetic variants at the GRIN1 gene and bipolar disorder in a German sample.
Psychiatr Genet. 2006 Oct;16(5):183-4. - Baghai TC, Binder EB, Schule C, Salyakina D, Eser D, Lucae S, Zwanzger P, Haberger C, Zill P, Ising M, Deiml T, Uhr M, Illig T, Wichmann HE, Modell S, Nothdurfter C, Holsboer F, Muller-Myhsok B, Moller HJ, Rupprecht R, Bondy B
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.
Mol Psychiatry. 2006 Nov;11(11):1003-15. Epub 2006 Aug 22. - Skowronek MH, Georgi A, Jamra RA, Schumacher J, Becker T, Schmael C, Paul T, Deschner M, Hofels S, Wulff M, Schwarz M, Klopp N, Illig T, Propping P, Cichon S, Noethen MM, Schulze TG, Rietschel M
No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample.
Psychiatr Genet. 2006 Dec;16(6):233-4. - Lingenhel A, Lhotta K, Neyer U, Heid IM, Rantner B, Kronenberg MF, Konig P, von Eckardstein A, Schober M, Dieplinger H, Kronenberg F
Role of the kidney in the metabolism of apolipoprotein A-IV: influence of the type of proteinuria.
J Lipid Res. 2006 Sep;47(9):2071-9. Epub 2006 Jun 20. - Lamina C, Meisinger C, Heid IM, Loewel H, Rantner B, Koenig W, Kronenberg F, KORA study group
Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up.
Eur Heart J. 2006 Nov;27(21):2580-7. Epub 2006 Sep 4. - Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrandt J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird N, Nenburg ME, Lange C, Christman MF
A common genetic variant 10 kb upstream of INSIG2 is associated with adult and childhood obesity.
Science. 2006 Apr 14;312(5771):279-83. - Herder C, Baumert J, Thorand B, Koenig W, de Jager W, Meisinger C, Illig T, Martin S, Kolb H
Chemokines as Risk Factors for Type 2 Diabetes. Results from the MONICA/KORA Augsburg Study 1984-2002
Diabetologia. 2006 May;49(5):921-929. Epub 2006 Mar 11. - Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE,
Marban E, O'donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
Nat Genet. 2006 Apr 30; - Schaeffer L, Gohlke H, Mueller M, Heid IM, Palmer LJ, Kompauer I, Demmelmair H, Illig T, Koletzko B, Heinrich J
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids.
Hum Mol Genet. 2006 May 2 - Holle R, Hochadel M, Reitmeir P, Meisinger C, Wichmann HE, KORA study group
Prolonged recruitment efforts in health surveys: effects on response, costs, and potential bias
Epidemiology. 2006 Nov;17(6):639-43 - Sedlmeier EM, Grallert H, Huth C, Lowel H, Herder C, Strassburger K, Giani G, Wichmann HE, Hauner H, Illig T, Rathmann W
Gene variants of monocyte chemoattractant protein 1 and components of metabolic syndrome in KORA S4, Augsburg
Eur J Endocrinol. 2007 Mar;156(3):377-85 - Akyol M, Jalilzadeh S, Sinner MF, Perz S, Beckmann BM, Gieger C, Illig T, Wichmann HE, Meitinger T, Kaab S, Pfeufer A
The common non-synonymous variant G38S of the KCNE1-(minK)-gene is not associated to QT interval in Central European Caucasians: results from the KORA study
Eur Heart J. 2007 Feb;28(3):305-9. Epub 2007 Jan 16 - Fisher E, Nitz I, Gieger C, Grallert H, Gohlke H, Lindner I, Dahm S, Boeing H, Burwinkel B, Rathmann W, Wichmann HE, Schrezenmeir J, Illig T, Doring F
Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations
Mol Nutr Food Res. 2007 Feb;51(2):178-84 - Marzi C, Huth C, Kolz M, Grallert H, Meisinger C, Wichmann HE, Rathmann W, Herder C, Illig T
Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys
Horm Metab Res. 2007 Jan;39(1):46-52 - Huth C, Siegert N, Meisinger C, Konig J, Kaab S, Wichmann HE, Doering A, KORA study group
Individuals with very low alcohol consumption: a heterogeneous group
J Stud Alcohol Drugs. 2007 Jan;68(1):6-10 - Vollmert C, Hahn S, Lamina C, Huth C, Kolz M, Schopfer-Wendels A, Mann K, Bongardt F, Mueller JC, Kronenberg F, Wichmann HE, Herder C, Holle R, Lowel H, Illig T, Janssen OE, KORA study group
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians
Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E836-44. Epub 2006 Nov 14 - Kolleritz B, Fliser D, Heid IM, Ritz E, Kronenberg F
Sex-specific association of adiponectin as a predictor of progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study
Kidney Int. 2007 Jun;71(12):1279-86 - Kabesch M, Depner M, Dahmen I, Weiland SK, Vogelberg C, Niggemann B, Lau S, Illig T, Klopp N, Wahn U, Reinhardt D, von Mutius E, Nickel R
Polymorphisms in eosinophil pathway genes, asthma and atopy
Allergy. 2007 Apr;62(4):423-8 - Schirmbeck F, Georgi A, Strohmaier J, Schmael C, Knorr C, Jamra RA, Schumacher J, Becker T, Klopp N, Illig T, Wulf M, Schwarz M, Maier W, Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M
No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample
Psychiatr Genet. 2007 Apr;17(2):127 - Strohmaier J, Georgi A, Schirmbeck F, Schmael C, Jamra RA, Schumacher J, Becker T, Hofels S, Klopp N, Illig T, Propping P, Cichon S, Nothen MM, Rietschel M, Schulze TG
No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample
Psychiatr Genet. 2007 Apr;17(2):125 - Sedlacek K, Neureuther K, Mueller JC, Stark K, Fischer M, Baessler A, Reinhard W, Broeckel U, Lieb W, Erdmann J, Schunkert H, Riegger G, Illig T, Meitinger T, Hengstenberg C
Lymphotoxin-alpha and galectin-2 SNPs are not associated with myocardial infarction in two different German populations
J Mol Med. 2007 Sep;85(9):997-1004 - Depner M, Kormann MS, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Combadiere C, Kabesch M
CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children
Int Arch Allergy Immunol. 2007 May 15;144(1):91-94 - Nitz I, Fisher E, Grallert H, Yun Li, Gieger C, Rubin D, Boeing H, Spranger J, Lindner I, Schreiber S, Rathmann W, Gohlke H, Doering A, Wichmann HE, Schrezenmeir J, Doering F, Illig T
Association of Prostaglandin E Synthase 2 (PTGES2) Arg298His Polymorphism with Type 2 Diabetes in two German Study Populations
J Clin Endocrinol Metab. 2007 Aug;92(8):3183-8 - Winkelmann J, Schormair B, Lichtner P, Ripke S, Xiong L, Jalilzadeh S, Fulda S, Pütz B, Eckstein G, Hauk S, Trenkwalder C, Zimprich A, Stiasny-Kolster K, Oertel W, Bachmann CG, Paulus W, Peglau I, Eisensehr I, Montplaisir J, Turecki G, Rouleau G, Gieger C, Illig T, Wichmann HE, Holsboer F, Mueller-Myhsok B, Meitinger T
Genome-wide association study in restless legs syndrome identifies common variants in three genomic regions
Nat Genet. 2007 Aug;39(8):1000-6 - Jaremko M, Justenhoven C, Schroth W, Abraham BK, Fritz P, Vollmert C, Illig T, Simon W, Schwab M, Brauch H
Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and yclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer
Pharmacogenet Genomics. 2007 Jul;17(7):529-38 - Novak N, Yu CF, Bussmann C, Maintz L, Peng WM, Hart J, Hagemann T, Diaz-Lacava A, Baurecht HJ, Klopp N, Wagenpfeil S, Behrendt H, Bieber T, Ring J, Illig T, Weidinger S
Putative association of a TLR9 promoter polymorphism with atopic eczema
Allergy. 2007 Jul;62(7):766-72 - Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
Nature, 2007 Jul 26;448(7152):470-3 - Justenhoven C, Hamann U, Schubert F, Zapatka M, Pierl CB, Rabstein S, Selinski S, Mueller T, Ickstadt K, Gilbert M, Ko YD, Baisch C, Pesch B, Harth V, Bolt HM, Vollmert C, Illig T, Eils R, Dippon J, Brauch H
Breast cancer: a candidate gene approach across the estrogen metabolic pathway
Breast Cancer Res Treat. 2008 Mar; 108(1):137-49. Epub 2007 Jun 23 - Kramer U, Illig T, Grune T, Krutmann J, Esser C
Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype
Genes Immun. 2007 Sep;8(6):513-7 - Schoenborn V, Gohlke H, Heid IM, Illig T, Utermann G, Kronenberg F
Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff
Hum Mutat 2007, in press - Holzapfel C, Klopp N, Grallert H, Huth C, Gieger C, Meisinger C, Strassburger K, Giani G, Wichmann HE, Laumen H, Hauner H, Herder C, Rathmann W, Illig T
Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study)
Eur J Endocrinol. 2007 Sep;157(3):R1-R5 - Pauli S, Soker T, Klopp N, Illig T, Engel W, Graw J
Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene
Mol Vis. 2007 Jun 19;13:962-7 - Grallert H, Sedlmeier EM, Huth C, Kolz M, Heid IM, Meisinger C, Herder C, Strassburger K, Giani G, Kronenberg F, Wichmann HE, Adamski J, Paulweber B, Illig T, Rathmamn W
APOA5 variants: Role in the metabolic syndrome? Results from KORA S4 and SAPHIR, two population based studies
J Lipid Res. 2007 Dec; 48(12):2614-21. Epub 2007 Sep 3 - Georgi A, Jamra RA, Klein K, Villela AW, Schumacher J, Becker T, Paul T, Schmael C, Hofels S, Klopp N, Illig T, Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M
Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample
Psychiatr Genet. 2007 Oct;17(5):308-310 - Herder C, Klopp N, Baumert J, Mueller M, Khuseyinova N, Meisinger C, Martin S, Illig T, Koenig W, Thorand B
Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case-Cohort Study, 1984-2002
Diabetologia. 2007 Aug 22 - Kolz M, Koenig W , Mueller M, Andreani M, Greven S, Illig T, Khuseyinova N, Panagiotakos D, Pershagen G, Salomaa V, Sunyer J, Peters A
DNA variants, plasma levels and variability of C-reactive protein in myocardial infarction survivors: Results from the AIRGENE study
European Heart Journal. 2007 in press - Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, Konig IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H, WTCCC and the Cardiogenics Consortium
Genomewide association analysis of coronary artery disease
N Engl J Med. 2007 Aug 2;357(5):443-53 - Koch W, Hoppmann P, Michou E, Jung V, Pfeufer A, Mueller JC, Gieger C, Wichmann HE, Meitinger T, Schomig A, Kastrati A
Association of variants in the BAT1-NFKBIL1-LTA genomic region with protection against myocardial infarction in Europeans
Hum Mol Genet. 2007 Aug 1;16(15):1821-7 - Wichmann HE, Gieger C
Biobanks
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007 Feb;50(2):192-9 - Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn J, Laird N, Lenburg ME, Lange C, Christman MF
Response to Comments on A Common Genetic Variant Is Associated with Adult and Childhood Obesity
Science 2007. 315, 187e - Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen T, Scherag A, Pfeufer A, Meitinger T, Broenner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss S, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O´Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN
The Association of a SNP Upstream of INSIG2 with Body Mass Index is Peproduced in Several but Not All Cohorts
PLOS Genet 2007, 3(4): e61 - Hoffmann K, Mattheisen M, Dahm S, Nurnberg P, Roe C, Johnson J, Cox NJ, Wichmann HE, Wienker TF, Schulze J, Schwarz PE, Lindner TH
A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2
Diabetologia. 2007 Jul;50(7):1418-22 - Baessler A, Fischer M, Mayer B, Koehler M, Wiedmann S, Stark K, Doering A, Erdmann J, Riegger G, Schunkert H, Kwitek AE, Hengstenberg C
Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease
Hum Mol Genet. 2007 Apr 15;16(8):887-99 - Thorand B, Baumert J, Herder C, Meisinger C, Koenig W
Soluble thrombomodulin as a predictor of type 2 diabetes: results from the MONICA/KORA Augsburg case-cohort study, 1984-1998
Diabetologia. 2007 Mar;50(3):545-8 - Thorand B, Baumert J, Kolb H, Meisinger C, Chambless L, Koenig W, Herder C
Sex differences in the prediction of type 2 diabetes by inflammatory markers: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002
Diabetes Care. 2007 Apr;30(4):854-60 - Justenhoven C, Pierl CB, Haas S, Fischer HP, Baisch C, Hamann U, Harth V, Pesch B, Bruening T, Vollmert C, Illig T, Dippon J, Ko YD, Brauch H
The CYP1B1_1358_GG genotype is associated with estrogen receptor-negative breast cancer
Breast Cancer Res Treat, Stand 10/2007: Online first - Doering A, Gieger C, Mehta D, Gohlke H, Prokisch H, Coassin S, Fischer G, Henke K, Klopp N, Kronenberg F, Paulweber B, Pfeufer A, Rosskopf D, Voelzke H, Illig T, Meitinger T, Wichmann HE, Meisinger C
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects
Nat Genet 40(4), 430-436 (2008) - Freilinger T, Bevan S, Ripke S, Gschwendtner A, Lichtner P, Mueller-Myhsok B, Wichmann HE, Markus HS, Meitinger T, Dichgans M
Genetic Variation in the Lymphotoxin-Alpha Pathway and the Risk of Ischaemic Stroke in European Populations
Stroke, Stand 12/2007: Online first - Fuchs J, Mueller JC, Lichtner P, Schulte C, Munz M, Berg D, Wuellner U, Illig T, Sharma M, Gasser T
The transcription factor PITX3 is associated with sporadic Parkinson`s disease
Neurobiology Aging, Stand 10/2007: Epub ahead of print - Gibson J, Tapper W, Cox D, Zhang W, Pfeufer A, Gieger C, Wichmann HE, Kaeaeb S, Collins AR, Meitinger T, Morton N
A multimetric approach to analysis of genome-wide association by single markers and composite likelihood
PNAS 105(7), 2592-2597 (2008) - Heid IM, Vollmert C, Kronenberg F, Huth C, Ankerst DP, Luchner A, Hinney A, Broenner G, Wichmann HE, Illig T, Doering A, Hebebrand J
Association of the MC4R V103I Polymorphism With the Metabolic Syndrome: The KORA Study
Obesity 16(2), 369-376 (2008) - Herder C, Klopp N, Baumert J, Mueller M, Khuseyinova N, Meisinger C, Martin S, Illig T, Koenig W, Thorand B
Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case Cohort Study, 1984-2002
Diabetologia 51(2), 276-284 (2008) - Hinterseer M, Thomsen MB, Beckmann BM, Pfeufer A, Schimpf R, Wichmann HE, Steinbeck G, Vos MA, Kaeaeb S
Beat-To-Beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study
Eur Heart J 29, 185-190 (2008) - Justenhoven C, Hamann U, Schubert F, Zapatka M, Pierl CB, Rabstein S, Selinski S, Mueller T, Ickstadt K, Gilbert M, Ko YD, Baisch C, Pesch B, Harth V, Bolt HM, Vollmert C, Illig T, Eils R, Dippon J, Brauch H
Breast cancer: a candidate gene approach across the estrogen metabolic pathway
Breast Cancer Res Treat108, 137-149 (2008) - Kolz M, Baumert J, Mueller M, Khuseyinova N, Klopp N, Thorand B, Meisinger C, Herder C, Koenig W, Illig T
Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol
BMC Medical Genetics 9(1): 9 (2008) - Lasky-Su J, Lyon HN, Emilsson V, Thorleifson G, Thorsteinsdottir U, Stefansson K, Lazarus R, Klanderman B, Raby BA, Soto-Quiros ME, Avila L, Silverman EK, Celedón JC, Weiss ST, Heid IM, Kronenberg F, Vollmert C, Illig T, Wichmann HE, Fox CS, Levy D, O`Donnell CJ, Laird N, Ding X, McQueen Molony C, Schadt E, Butler J, Ardlie K, Hirschhorn J, Papoutsakis C, Dedoussis G, Lange C
On the replication of genetic associations: Timing can be everything!
Am J Hum Genet. 2008 Apr; 82(4):849-58 - Lieb W, Mayer B, Koenig IR, Borwitzky I, Goetz A, Kain S, Hengstenberg C, Linsel-Nitschke P, Fischer M, Doering A, Wichmann HE, Meitinger T, Kreutz R, Ziegler A, Schunkert H, Erdmann J
Lack of Association Between the MEF2A Gene and Myocardial Infarction
Circulation 117, 185-191 (2008) - Luca D, Ringquist S, Klei L, Lee AB, Gieger C, Wichmann HE, Schreiber S, Krawczak M, Lu Y, Styche A, Devlin B, Roeder K, Trucco M
On the Use of General Control Samples for Genome-wide Association Studies: Genetic Matching Highlights Causal Variants
Am J Hum Genet 82, 453-463 (2008) (+ Online Data Supplement) - Luecking CB, Lichtner P, Dichgans M, Illig T, Gieger C, Berg D, Gasser T
Polymorphisms in the proteasomal subunit alpha4 are not associated with Parkinson`s disease
J Neurol 255, 441-442 (2008) - Novak N, Baurecht H, Schaefer T, Rodriguez E, Wagenpfeil S, Klopp N, Heinrich J, Behrendt H, Ring J, Wichmann HE, Illig T, Weidinger S
Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel
J Invest Dermatology, Stand 12/2007: online first erschienen - Rosenberger A, Illig T, Korb K, Klopp N, Zietemann V, Woelke G, Meese E, Sybrecht G, Kronenberg F, Cebulla M, Degen M, Drings P, Groeschel A, Konietzko N, Kreymborg K, Haeuszlinger K, Hoeffken G, Jilge B, Ko YD, Morr H, Schmidt C, Taeuscher D, Bickeboeller H, Wichmann HE
Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years
BMC Cancer. 2008 Feb 25; 8:60. Online first erschienen - Schedel M, Pinto LA, Schaub B, Rosenstiel P, Cherkasov D, Cameron L, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Lohoff M, Kabesch M
IRF-1 Gene Variations Influence IgE Regulation and Atopy
Am J Respir Crit Care Med 177, 613-621 (2008) - Schneider J, Illig T, Rosenberger A, Bickeboeller H, Wichmann HE
Detection of ATM Gene Mutations in Young Lung Cancer Patients: A Population-based Control Study
Arch Med Res 39, 226-231 (2008) - Sinner MF, Pfeufer A, Akyol M, Beckmann BM, Hinterseer M, Wacker A, Perz S, Sauter W, Illig T, Naebauer M, Schmitt C, Wichmann HE, Schoemig A, Steinbeck G, Meitinger T, Kaeaeb S
The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG)
Eur Heart J. 2008 Apr; 29(7):907-914. Epub 2008 Jan 25 - Wiedmann S, Fischer M, Koehler M, Neureuther K, Stark K, Riegger G, Doering A, Hengstenberg C, Baessler A
Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans
Diabetes 57(1), 209-217 (2008) - Winkelmann J, Lichtner P, Schormair B, Uhr M, Hauk S, Stiasny-Kolster K, Trenkwalder C, Paulus W, Peglau I, Eisensehr I, Illig T, Wichmann HE, Pfister H, Golic J, Bettecken T, Puetz B, Holsboer F, Meitinger T, Mueller-Myhsok B
Variants in the Neuronal Nitric Oxide Synthase (nNOS, NOS1) Gene are Associated with Restless Legs Syndrome
Mov Disord 23(3), 350-358 (2008) - Yuille M, van Ommen GJ, Bréchot C, Cambon-Thomsen A, Dagher G, Landegren U, Litton JE, Pasterk M, Peltonen L, Taussig M, Wichmann HE, Zatloukal K
Biobanking for Europe
Brief Bioinformatics 9(1), 14-24 (2008)
